Searchable abstracts of presentations at key conferences in endocrinology

ea0019oc35 | Thyroid, reproduction and endocrine tumours | SFEBES2009

Bio-informatic identification of novel endocrine markers of gestational disease in the human placenta

Karanam V , Anim-Nyame N , Page N

Searching for novel endocrine markers involved in gestational disease (e.g. pre-eclampsia, foetal growth restriction, pre-term labour) remains a challenge. Nonetheless, the placenta is a very useful target tissue as it provides a repository of gene expression transcripts that are uniquely expressed during pregnancy. Here, we have used bio-informatic approaches to identify expressed sequence tag (EST) clusters differentially expressed between 1st trimester and term placentae. T...